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Dementia: Study identifies drug which could slow cognitive decline – ‘Promising’

The study, led by Dr Lucy Vivash, was published in the journal Alzheimer’s and Dementia: Translational Research and Clinical Interventions.

According to Dr Vivash, sodium selenate upregulates an enzyme in the brain that effectively breaks down the tau protein.

She said: “We have previously shown, in a Phase 2 trial, that sodium selenate given to patients with mild to moderate Alzheimer’s Disease resulted in less neurodegeneration than in those who did not.”

The patients with higher levels of selenium, a breakdown product of sodium selenate, in their blood showed less cognitive decline during the trial.



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